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Distinct metabolic features in the plasma of patients with silicosis and dust-exposed workers in China: a case-control study

Distinct metabolic features in the plasma of patients…

Silicosis is a progressive pneumoconiosis characterised by interstitial fibrosis following publicity to silica mud. The function of metabolic dysregulation in the pathogenesis of silicosis has not been investigated in element. This study aimed to establish…
Isomerization of trans-3-methylglutaconic acid

Isomerization of trans-3-methylglutaconic acid

3-Methylglutaconic (3MGC) aciduria is a typical phenotypic function of a rising quantity of inborn errors of metabolism. "Primary" 3MGC aciduria is attributable to deficiencies in leucine pathway enzymes whereas "secondary" 3MGC aciduria outcomes from inborn…
Rapid Denaturing Organic Digestion Method for Targeted Protein Identification and Characterization

Rapid Denaturing Organic Digestion Method for Targeted Protein…

Bottom-up mass spectrometry-based protein evaluation strategies using protease digestion are routinely used to establish and characterize proteins with excessive specificity and sensitivity. Method efficiency is usually measured by sequence protection functionality and the entire variety of attribute…