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Isomerization of trans-3-methylglutaconic acid

Isomerization of trans-3-methylglutaconic acid

3-Methylglutaconic (3MGC) aciduria is a typical phenotypic function of a rising quantity of inborn errors of metabolism. “Primary” 3MGC aciduria is attributable to deficiencies in leucine pathway enzymes whereas “secondary” 3MGC aciduria outcomes from inborn errors of metabolism that impression mitochondrial vitality manufacturing. The metabolic precursor of 3MGC acid is trans-3MGC CoA, an intermediate within the leucine catabolism pathway. Gas chromatography-mass spectrometry (GC-MS) evaluation of commercially out there trans-3MGC acid yielded a combination of cis and trans isomers whereas 1H-NMR spectroscopy of trans-3MGC acid at 25°C supplied no proof for the cis isomer.

When trans-3MGC acid was incubated beneath circumstances used for pattern derivatization previous to GC-MS (however with no trimethylsilane added), 1H-NMR spectroscopy supplied proof of trans to cis isomerization. Incubation of trans-3MGC acid at 37°C resulted in time-dependent isomerization to cis-3MGC acid. Cis-3MGC acid behaved in the same method besides that, beneath equivalent incubation circumstances, much less isomerization occurred. In settlement with these experimental outcomes, molecular modeling research supplied proof that the vitality minimized construction of cis-3MGC acid is four kJ/mol extra secure than that for trans-3MGC acid.

The knowledge introduced are according to the incidence of each diastereomers in urine samples of topics with 3MGC aciduria. Quantification of iron is a crucial step to evaluate the iron burden in sufferers affected by iron overload illnesses, in addition to super worth in understanding the underlying function of iron within the pathophysiology of these illnesses. Current iron willpower of complete or labile iron, requires in depth pattern dealing with and specialised devices, while being time consuming and laborious. Moreover, there’s minimal to no overlap between complete iron and labile iron quantification methodologies-i.e. requiring totally separate protocols, strategies and devices. Herein, we report a unified-ferene (u-ferene) assay that allows a 2-in-1 quantification of each labile and complete iron from the identical preparation of a organic specimen.

MANTI: Automated Annotation of Protein N-Termini for Rapid Interpretation of N-Terminome Data Sets

Site-specific proteolytic processing is a crucial, irreversible post-translational protein modification with implications in lots of illnesses. Enrichment of protein N-terminal peptides adopted by mass spectrometry-based identification and quantification allows proteome-wide characterization of proteolytic processes and protease substrates however is challenged by the shortage of particular annotation instruments. A typical downside is, for instance, ambiguous matches of recognized peptides to a number of protein entries within the databases used for identification.

We developed MaxQuant Advanced N-termini Interpreter (MANTI), a standalone Perl software program with an optionally available graphical consumer interface that validates and annotates N-terminal peptides recognized by database searches with the favored MaxQuant software program bundle by integrating data from a number of knowledge sources. MANTI makes use of numerous annotation data in a multistep determination course of to assign a conservative most well-liked protein entry for every N-terminal peptide, enabling automated classification in line with the doubtless origin and determines important adjustments in N-terminal peptide abundance. Auxiliary R scripts included within the software program bundle summarize and visualize key facets of the information.

To showcase the utility of MANTI, we generated two large-scale TAILS N-terminome knowledge units from two completely different animal fashions of chemically and genetically induced kidney illness, puromycin adenonucleoside-treated rats (PAN), and heterozygous Wilms Tumor protein 1 mice (WT1). MANTI enabled fast validation and autonomous annotation of >10 000 recognized terminal peptides, revealing novel proteolytic proteoforms in 905 and 644 proteins, respectively. Quantitative evaluation indicated that proteolytic actions with related sequence specificity are concerned within the pathogenesis of kidney harm and proteinuria in each fashions, whereas coagulation processes and complement activation have been particularly induced after chemical harm.

Isomerization of trans-3-methylglutaconic acid

ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ

Previously, we recognized missense mutations in CCNF which can be causative of familial and sporadic amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Hallmark options of these illnesses embody the build-up of insoluble protein aggregates in addition to the mislocalisation of proteins reminiscent of TDP-43. In latest years, the dysregulation of SFPQ has additionally emerged as a pathological hallmark of ALS/FTD. CCNF encodes for the protein cyclin F, a substrate recognition part of an E3-ubiquitin ligase. We have beforehand proven that ALS/FTD-linked mutations in CCNF trigger disruptions to general protein homeostasis that results in a build-up of Ok48-linked ubiquitylated proteins in addition to defects in autophagic equipment.

To examine additional processes that could be affected by cyclin F, we used a protein-proximity ligation methodology, often known as BioID, customary immunoprecipitations and mass spectrometry (MS) to establish novel interplay companions of cyclin F and infer additional course of that could be affected by the ALS/FTD-causing mutation. Results display that cyclin F intently associates with proteins concerned with RNA metabolism in addition to a quantity of RNA binding proteins beforehand linked to ALS/FTD, together with splicing issue proline and glutamine wealthy (SFPQ).

Smad Interacting Protein 1 (ZEB2) (C-term) rabbit polyclonal antibody, Purified

AP31202PU-N 50 µg Ask for price

Smad Interacting Protein 1 (ZEB2) (N-term) rabbit polyclonal antibody, Purified

AP31272PU-N 50 µl Ask for price

Rabbit polyclonal antibody to NOSIP (nitric oxide synthase interacting protein)

TA308380 100 µl Ask for price

MLX interacting protein (MLXIP) (N-term) rabbit polyclonal antibody, Aff - Purified

AP52708PU-N 400 µl Ask for price

Rabbit Polyclonal antibody to ARA9 (aryl hydrocarbon receptor interacting protein)

TA308832 100 µl Ask for price

Rabbit polyclonal antibody to TOK-1 alpha (BRCA2 and CDKN1A interacting protein)

TA308557 100 µl Ask for price

Smad Interacting Protein 1 (ZEB2) (C-term) rabbit polyclonal antibody, Aff - Purified

AP54642PU-N 400 µl Ask for price

Rabbit Polyclonal antibody to PPFIBP2 (PTPRF interacting protein, binding protein 2 (liprin beta 2))

TA308142 100 µl Ask for price

RPA Interacting Protein Antibody

24482-100ul 100ul
EUR 468

RPA Interacting Protein Antibody

24483-100ul 100ul
EUR 468

RPA Interacting Protein Antibody

4013-002mg 0.02 mg
EUR 206.18
Description: RPA Interacting Protein Antibody: Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.

RPA Interacting Protein Antibody

4013-01mg 0.1 mg
EUR 523.7
Description: RPA Interacting Protein Antibody: Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.

RPA Interacting Protein Antibody

4015-002mg 0.02 mg
EUR 206.18
Description: RPA Interacting Protein Antibody: Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.

RPA Interacting Protein Antibody

4015-01mg 0.1 mg
EUR 523.7
Description: RPA Interacting Protein Antibody: Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.

Rpa Interacting Protein Antibody

20-abx115340
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

RPA Interacting Protein Antibody

24482 100ul
EUR 479

RPA Interacting Protein Antibody

24483 100ul
EUR 479

Rabbit Polyclonal antibody to VCPIP1 (valosin containing protein (p97)/p47 complex interacting protein 1)

TA309036 100 µl Ask for price

Rabbit polyclonal antibody to TNNI3K (TNNI3 interacting kinase)

TA308400 100 µl Ask for price

Toll Interacting Protein (TOLLIP) Polyclonal Antibody

CAU23851-100ul 100ul
EUR 229.4

Toll Interacting Protein (TOLLIP) Polyclonal Antibody

CAU23851-200ul 200ul
EUR 287.3

Toll Interacting Protein (TOLLIP) Polyclonal Antibody

CAU23852-100ul 100ul
EUR 222.7

Toll Interacting Protein (TOLLIP) Polyclonal Antibody

CAU23852-200ul 200ul
EUR 278.9

Rabbit Polyclonal antibody to MID1IP1 (MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish)))

TA309030 100 µl Ask for price

Polyclonal Antibody to Toll Interacting Protein (TOLLIP)

PAC803Hu01 100ul
EUR 232

Polyclonal Antibody to Toll Interacting Protein (TOLLIP)

PAC803Mu01 100ul
EUR 239

Toll Interacting Protein (TOLLIP) Polyclonal Antibody (Human)

4-PAC803Hu01
  • EUR 286.80
  • EUR 2869.20
  • EUR 717.60
  • EUR 358.80
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Toll Interacting Protein (TOLLIP)

Polyclonal HSC70 Interacting Protein HIP (ST13) Antibody

APR16725G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HSC70 Interacting Protein HIP (ST13) . This antibody is tested and proven to work in the following applications:

Huntingtin Interacting Protein 2 (HIP2) Polyclonal Antibody

CAU22783-100ul 100ul
EUR 235.2

Huntingtin Interacting Protein 2 (HIP2) Polyclonal Antibody

CAU22783-200ul 200ul
EUR 294

Fms interacting protein (FMIP) [domain 1] polyclonal antibody

ABP-PAB-11638 100 ug Ask for price

Fms interacting protein (FMIP) [domain 2] polyclonal antibody

ABP-PAB-11639 100 ug Ask for price

Toll Interacting Protein (TOLLIP) Polyclonal Antibody (Human), PE

4-PAC803Hu01-PE
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Toll Interacting Protein (TOLLIP). This antibody is labeled with PE.

Toll Interacting Protein (TOLLIP) Polyclonal Antibody (Human), APC

4-PAC803Hu01-APC
  • EUR 399.60
  • EUR 3735.60
  • EUR 1046.40
  • EUR 507.60
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Toll Interacting Protein (TOLLIP). This antibody is labeled with APC.

Toll Interacting Protein (TOLLIP) Polyclonal Antibody (Human), Cy3

4-PAC803Hu01-Cy3
  • EUR 483.60
  • EUR 4930.80
  • EUR 1345.20
  • EUR 627.60
  • EUR 294.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Toll Interacting Protein (TOLLIP). This antibody is labeled with Cy3.

Toll Interacting Protein (TOLLIP) Polyclonal Antibody (Human), HRP

4-PAC803Hu01-HRP
  • EUR 366.00
  • EUR 3256.80
  • EUR 926.40
  • EUR 459.60
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Toll Interacting Protein (TOLLIP). This antibody is labeled with HRP.

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody

CAU21098-100ul 100ul
EUR 265.9
Description: polyclonal

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody

CAU21098-200ul 200ul
EUR 332.6
Description: polyclonal

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody

CAU21099-100ul 100ul
EUR 258.2
Description: polyclonal

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody

CAU21099-200ul 200ul
EUR 322.6
Description: polyclonal

Polyclonal Antibody to Huntingtin Interacting Protein 2 (HIP2)

PAE601Hu01 100ul
EUR 245

Toll Interacting Protein (TOLLIP) Polyclonal Antibody (Human), FITC

4-PAC803Hu01-FITC
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Toll Interacting Protein (TOLLIP). This antibody is labeled with FITC.

Huntingtin Interacting Protein 2 (HIP2) Polyclonal Antibody (Human)

4-PAE601Hu01
  • EUR 296.40
  • EUR 3012.00
  • EUR 750.00
  • EUR 372.00
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Huntingtin Interacting Protein 2 (HIP2)

Toll Interacting Protein (TOLLIP) Polyclonal Antibody (Human, Mouse)

4-PAC803Mu01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Toll Interacting Protein (TOLLIP)

Fibrous Sheath Interacting Protein 1 (FSIP1) Polyclonal Antibody

CAU21804-100ul 100ul
EUR 255.4

Fibrous Sheath Interacting Protein 1 (FSIP1) Polyclonal Antibody

CAU21804-200ul 200ul
EUR 319.2

Fibrous Sheath Interacting Protein 1 (FSIP1) Polyclonal Antibody

CAU21805-100ul 100ul
EUR 235.2

Fibrous Sheath Interacting Protein 1 (FSIP1) Polyclonal Antibody

CAU21805-200ul 200ul
EUR 294

Catenin Beta Interacting Protein 1 (CTNNbIP1) Polyclonal Antibody

CAU22635-100ul 100ul
EUR 241.9

Catenin Beta Interacting Protein 1 (CTNNbIP1) Polyclonal Antibody

CAU22635-200ul 200ul
EUR 302.4

Catenin Beta Interacting Protein 1 (CTNNbIP1) Polyclonal Antibody

CAU22636-100ul 100ul
EUR 235.2

Catenin Beta Interacting Protein 1 (CTNNbIP1) Polyclonal Antibody

CAU22636-200ul 200ul
EUR 294

RPA Interacting Protein

20-abx262685
  • EUR 393.60
  • EUR 7676.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Polyclonal Antibody to Kv Channel Interacting Protein 3 (KCNIP3)

PAH763Ra01 100ul
EUR 266

Polyclonal Antibody to Torsin A Interacting Protein 2 (TOR1AIP2)

PAR170Hu01 100ul
EUR 269

Polyclonal Antibody to Torsin A Interacting Protein 2 (TOR1AIP2)

PAR170Mu01 100ul
EUR 277

Thyroid receptor interacting protein 15 (TRIP15) polyclonal antibody

ABP-PAB-10139 100 ug Ask for price

Synuclein Alpha Interacting Protein 1 (SNCaIP1) Polyclonal Antibody

CAU23800-100ul 100ul
EUR 255.4

Synuclein Alpha Interacting Protein 1 (SNCaIP1) Polyclonal Antibody

CAU23800-200ul 200ul
EUR 319.2

Huntingtin Interacting Protein 1 Related Protein (HIP1R) Polyclonal Antibody

CAU24162-100ul 100ul
EUR 235.2

Huntingtin Interacting Protein 1 Related Protein (HIP1R) Polyclonal Antibody

CAU24162-200ul 200ul
EUR 294

Huntingtin Interacting Protein 2 (HIP2) Polyclonal Antibody (Human), PE

4-PAE601Hu01-PE
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Huntingtin Interacting Protein 2 (HIP2). This antibody is labeled with PE.

Fibrous Sheath Interacting Protein 1 (FSIP1) Polyclonal Antibody (Rat)

4-PAJ086Ra01
  • EUR 310.80
  • EUR 3249.60
  • EUR 804.00
  • EUR 393.60
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Fibrous Sheath Interacting Protein 1 (FSIP1)

Toll Interacting Protein (TOLLIP) Polyclonal Antibody (Human), APC-Cy7

4-PAC803Hu01-APC-Cy7
  • EUR 656.40
  • EUR 7327.20
  • EUR 1948.80
  • EUR 872.40
  • EUR 372.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Toll Interacting Protein (TOLLIP). This antibody is labeled with APC-Cy7.

Toll Interacting Protein (TOLLIP) Polyclonal Antibody (Human, Mouse), APC

4-PAC803Mu01-APC
  • EUR 408.00
  • EUR 3843.60
  • EUR 1072.80
  • EUR 518.40
  • EUR 260.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Toll Interacting Protein (TOLLIP). This antibody is labeled with APC.

Toll Interacting Protein (TOLLIP) Polyclonal Antibody (Human, Mouse), Cy3

4-PAC803Mu01-Cy3
  • EUR 493.20
  • EUR 5074.80
  • EUR 1381.20
  • EUR 642.00
  • EUR 297.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Toll Interacting Protein (TOLLIP). This antibody is labeled with Cy3.

Toll Interacting Protein (TOLLIP) Polyclonal Antibody (Human, Mouse), HRP

4-PAC803Mu01-HRP
  • EUR 373.20
  • EUR 3350.40
  • EUR 949.20
  • EUR 469.20
  • EUR 246.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Toll Interacting Protein (TOLLIP). This antibody is labeled with HRP.

Toll Interacting Protein (TOLLIP) Polyclonal Antibody (Human, Mouse), PE

4-PAC803Mu01-PE
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Toll Interacting Protein (TOLLIP). This antibody is labeled with PE.

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody (Human)

4-PAR170Hu01
  • EUR 313.20
  • EUR 3280.80
  • EUR 811.20
  • EUR 396.00
  • EUR 264.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Torsin A Interacting Protein 2 (TOR1AIP2)

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody (Mouse)

4-PAR170Mu01
  • EUR 319.20
  • EUR 3375.60
  • EUR 832.80
  • EUR 404.40
  • EUR 266.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Torsin A Interacting Protein 2 (TOR1AIP2)

Polyclonal Antibody to Catenin Beta Interacting Protein 1 (CTNNbIP1)

PAE898Hu01 100ul
EUR 245

Polyclonal Antibody to Catenin Beta Interacting Protein 1 (CTNNbIP1)

PAE898Mu01 100ul
EUR 252

Polyclonal Antibody to Fibrous Sheath Interacting Protein 1 (FSIP1)

PAJ086Hu01 100ul
EUR 245

Polyclonal Antibody to Fibrous Sheath Interacting Protein 1 (FSIP1)

PAJ086Ra01 100ul
EUR 266

Homeodomain Interacting Protein Kinase 2 (HIPK2) Polyclonal Antibody

CAU22482-100ul 100ul
EUR 235.2

Homeodomain Interacting Protein Kinase 2 (HIPK2) Polyclonal Antibody

CAU22482-200ul 200ul
EUR 294

Homeodomain Interacting Protein Kinase 1 (HIPK1) Polyclonal Antibody

CAU24161-100ul 100ul
EUR 235.2

Homeodomain Interacting Protein Kinase 1 (HIPK1) Polyclonal Antibody

CAU24161-200ul 200ul
EUR 294

Glutamate Receptor Interacting Protein 1 (GRIP1) Polyclonal Antibody

CAU25376-100ul 100ul
EUR 222.7

Glutamate Receptor Interacting Protein 1 (GRIP1) Polyclonal Antibody

CAU25376-200ul 200ul
EUR 278.9

Glutamate Receptor Interacting Protein 1 (GRIP1) Polyclonal Antibody

CAU25377-100ul 100ul
EUR 222.7

Glutamate Receptor Interacting Protein 1 (GRIP1) Polyclonal Antibody

CAU25377-200ul 200ul
EUR 278.9

Nitric Oxide Synthase Interacting Protein (NOSIP) Polyclonal Antibody

CAU28095-100ul 100ul
EUR 211.2

Nitric Oxide Synthase Interacting Protein (NOSIP) Polyclonal Antibody

CAU28095-200ul 200ul
EUR 263.8

Huntingtin-associated protein interacting protein (HAPIP) polyclonal antibody

ABP-PAB-10621 100 ug Ask for price

Huntingtin Interacting Protein 2 (HIP2) Polyclonal Antibody (Human), APC

4-PAE601Hu01-APC
  • EUR 414.00
  • EUR 3930.00
  • EUR 1094.40
  • EUR 528.00
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Huntingtin Interacting Protein 2 (HIP2). This antibody is labeled with APC.

Huntingtin Interacting Protein 2 (HIP2) Polyclonal Antibody (Human), Cy3

4-PAE601Hu01-Cy3
  • EUR 502.80
  • EUR 5190.00
  • EUR 1410.00
  • EUR 654.00
  • EUR 301.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Huntingtin Interacting Protein 2 (HIP2). This antibody is labeled with Cy3.

Huntingtin Interacting Protein 2 (HIP2) Polyclonal Antibody (Human), FITC

4-PAE601Hu01-FITC
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Huntingtin Interacting Protein 2 (HIP2). This antibody is labeled with FITC.

Huntingtin Interacting Protein 2 (HIP2) Polyclonal Antibody (Human), HRP

4-PAE601Hu01-HRP
  • EUR 379.20
  • EUR 3426.00
  • EUR 968.40
  • EUR 477.60
  • EUR 247.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Huntingtin Interacting Protein 2 (HIP2). This antibody is labeled with HRP.

Fibrous Sheath Interacting Protein 1 (FSIP1) Polyclonal Antibody (Human)

4-PAJ086Hu01
  • EUR 296.40
  • EUR 3012.00
  • EUR 750.00
  • EUR 372.00
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Fibrous Sheath Interacting Protein 1 (FSIP1)

Toll Interacting Protein (TOLLIP) Polyclonal Antibody (Human, Mouse), FITC

4-PAC803Mu01-FITC
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Toll Interacting Protein (TOLLIP). This antibody is labeled with FITC.

Huntingtin Interacting Protein 12 (HIP12) Polyclonal Antibody (Human, Pig)

4-PAC525Hu01
  • EUR 296.40
  • EUR 3012.00
  • EUR 750.00
  • EUR 372.00
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Pig Huntingtin Interacting Protein 12 (HIP12)

Polyclonal Antibody to Synuclein Alpha Interacting Protein 1 (SNCaIP1)

PAC859Ra01 100ul
EUR 266

Toll Interacting Protein (TOLLIP) Polyclonal Antibody (Human), Biotinylated

4-PAC803Hu01-Biotin
  • EUR 363.60
  • EUR 2809.20
  • EUR 836.40
  • EUR 442.80
  • EUR 259.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Toll Interacting Protein (TOLLIP). This antibody is labeled with Biotin.

Cannabinoid Receptor Interacting Protein 1 (CNRIP1) Polyclonal Antibody

CAU31731-100ul 100ul
EUR 235.2

Cannabinoid Receptor Interacting Protein 1 (CNRIP1) Polyclonal Antibody

CAU31731-200ul 200ul
EUR 294

Aryl Hydrocarbon Receptor Interacting Protein (AIP) Polyclonal Antibody

CAU24445-100ul 100ul
EUR 235.2

Aryl Hydrocarbon Receptor Interacting Protein (AIP) Polyclonal Antibody

CAU24445-200ul 200ul
EUR 294

Polyclonal Antibody to Huntingtin Interacting Protein 1 Related Protein (HIP1R)

PAC525Hu01 100ul
EUR 245

Rabbit Polyclonal antibody to Liprin alpha 1 (protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1)

TA308315 100 µl Ask for price

Fibrous Sheath Interacting Protein 1 (FSIP1) Polyclonal Antibody (Rat), PE

4-PAJ086Ra01-PE
  • EUR 373.20
  • EUR 3427.20
  • EUR 964.80
  • EUR 471.60
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Fibrous Sheath Interacting Protein 1 (FSIP1). This antibody is labeled with PE.

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody (Human), PE

4-PAR170Hu01-PE
  • EUR 375.60
  • EUR 3460.80
  • EUR 973.20
  • EUR 475.20
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Torsin A Interacting Protein 2 (TOR1AIP2). This antibody is labeled with PE.

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody (Mouse), PE

4-PAR170Mu01-PE
  • EUR 382.80
  • EUR 3565.20
  • EUR 998.40
  • EUR 486.00
  • EUR 246.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Torsin A Interacting Protein 2 (TOR1AIP2). This antibody is labeled with PE.

Synuclein Alpha Interacting Protein 1 (SNCaIP1) Polyclonal Antibody (Rat)

4-PAC859Ra01
  • EUR 310.80
  • EUR 3249.60
  • EUR 804.00
  • EUR 393.60
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Synuclein Alpha Interacting Protein 1 (SNCaIP1)

Catenin Beta Interacting Protein 1 (CTNNbIP1) Polyclonal Antibody (Human)

4-PAE898Hu01
  • EUR 296.40
  • EUR 3012.00
  • EUR 750.00
  • EUR 372.00
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Catenin Beta Interacting Protein 1 (CTNNbIP1)

Catenin Beta Interacting Protein 1 (CTNNbIP1) Polyclonal Antibody (Mouse)

4-PAE898Mu01
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Catenin Beta Interacting Protein 1 (CTNNbIP1)

Polyclonal Antibody to Homeodomain Interacting Protein Kinase 2 (HIPK2)

PAF477Hu01 100ul
EUR 245

Polyclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1)

PAB753Hu01 100ul
EUR 232

Polyclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1)

PAB753Hu02 100ul
EUR 232

Polyclonal Antibody to Nitric Oxide Synthase Interacting Protein (NOSIP)

PAA330Hu01 100ul
EUR 220

Programmed Cell Death Protein 6 Interacting Protein (PDCD6IP) Polyclonal Antibody

CAU26274-100ul 100ul
EUR 229.4

Programmed Cell Death Protein 6 Interacting Protein (PDCD6IP) Polyclonal Antibody

CAU26274-200ul 200ul
EUR 287.3

Programmed Cell Death Protein 6 Interacting Protein (PDCD6IP) Polyclonal Antibody

CAU26275-100ul 100ul
EUR 222.7

Programmed Cell Death Protein 6 Interacting Protein (PDCD6IP) Polyclonal Antibody

CAU26275-200ul 200ul
EUR 278.9

Protein Interacting With C Kinase 1 (PICK1) Polyclonal Antibody

CAU26816-100ul 100ul
EUR 217.9

Protein Interacting With C Kinase 1 (PICK1) Polyclonal Antibody

CAU26816-200ul 200ul
EUR 272.2

Fibrous Sheath Interacting Protein 1 (FSIP1) Polyclonal Antibody (Human), PE

4-PAJ086Hu01-PE
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Fibrous Sheath Interacting Protein 1 (FSIP1). This antibody is labeled with PE.

Fibrous Sheath Interacting Protein 1 (FSIP1) Polyclonal Antibody (Rat), APC

4-PAJ086Ra01-APC
  • EUR 436.80
  • EUR 4254.00
  • EUR 1176.00
  • EUR 560.40
  • EUR 272.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Fibrous Sheath Interacting Protein 1 (FSIP1). This antibody is labeled with APC.

Fibrous Sheath Interacting Protein 1 (FSIP1) Polyclonal Antibody (Rat), Cy3

4-PAJ086Ra01-Cy3
  • EUR 532.80
  • EUR 5622.00
  • EUR 1518.00
  • EUR 697.20
  • EUR 313.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Fibrous Sheath Interacting Protein 1 (FSIP1). This antibody is labeled with Cy3.

Fibrous Sheath Interacting Protein 1 (FSIP1) Polyclonal Antibody (Rat), FITC

4-PAJ086Ra01-FITC
  • EUR 373.20
  • EUR 3427.20
  • EUR 964.80
  • EUR 471.60
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Fibrous Sheath Interacting Protein 1 (FSIP1). This antibody is labeled with FITC.

Fibrous Sheath Interacting Protein 1 (FSIP1) Polyclonal Antibody (Rat), HRP

4-PAJ086Ra01-HRP
  • EUR 398.40
  • EUR 3706.80
  • EUR 1039.20
  • EUR 505.20
  • EUR 255.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Fibrous Sheath Interacting Protein 1 (FSIP1). This antibody is labeled with HRP.

Huntingtin Interacting Protein 12 (HIP12) Polyclonal Antibody (Human, Pig), PE

4-PAC525Hu01-PE
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Pig Huntingtin Interacting Protein 12 (HIP12). This antibody is labeled with PE.

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody (Human), APC

4-PAR170Hu01-APC
  • EUR 440.40
  • EUR 4297.20
  • EUR 1186.80
  • EUR 564.00
  • EUR 273.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Torsin A Interacting Protein 2 (TOR1AIP2). This antibody is labeled with APC.

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody (Human), Cy3

4-PAR170Hu01-Cy3
  • EUR 536.40
  • EUR 5679.60
  • EUR 1532.40
  • EUR 702.00
  • EUR 315.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Torsin A Interacting Protein 2 (TOR1AIP2). This antibody is labeled with Cy3.

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody (Human), FITC

4-PAR170Hu01-FITC
  • EUR 375.60
  • EUR 3460.80
  • EUR 973.20
  • EUR 475.20
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Torsin A Interacting Protein 2 (TOR1AIP2). This antibody is labeled with FITC.

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody (Human), HRP

4-PAR170Hu01-HRP
  • EUR 400.80
  • EUR 3744.00
  • EUR 1047.60
  • EUR 508.80
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Torsin A Interacting Protein 2 (TOR1AIP2). This antibody is labeled with HRP.

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody (Mouse), APC

4-PAR170Mu01-APC
  • EUR 448.80
  • EUR 4426.80
  • EUR 1219.20
  • EUR 577.20
  • EUR 278.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Torsin A Interacting Protein 2 (TOR1AIP2). This antibody is labeled with APC.

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody (Mouse), Cy3

4-PAR170Mu01-Cy3
  • EUR 548.40
  • EUR 5852.40
  • EUR 1575.60
  • EUR 720.00
  • EUR 320.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Torsin A Interacting Protein 2 (TOR1AIP2). This antibody is labeled with Cy3.

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody (Mouse), FITC

4-PAR170Mu01-FITC
  • EUR 382.80
  • EUR 3565.20
  • EUR 998.40
  • EUR 486.00
  • EUR 246.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Torsin A Interacting Protein 2 (TOR1AIP2). This antibody is labeled with FITC.

Torsin A Interacting Protein 2 (TOR1AIP2) Polyclonal Antibody (Mouse), HRP

4-PAR170Mu01-HRP
  • EUR 409.20
  • EUR 3855.60
  • EUR 1076.40
  • EUR 519.60
  • EUR 260.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Torsin A Interacting Protein 2 (TOR1AIP2). This antibody is labeled with HRP.

Homeodomain Interacting Protein Kinase 2 (HIPK2) Polyclonal Antibody (Human)

4-PAF477Hu01
  • EUR 296.40
  • EUR 3012.00
  • EUR 750.00
  • EUR 372.00
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 2 (HIPK2)

Nitric Oxide Synthase Interacting Protein (NOSIP) Polyclonal Antibody (Human)

4-PAA330Hu01
  • EUR 278.40
  • EUR 2726.40
  • EUR 685.20
  • EUR 345.60
  • EUR 248.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Nitric Oxide Synthase Interacting Protein (NOSIP)

Notably, the overexpression of cyclin F(S621G) led to the aggregation and altered subcellular distribution of SFPQ in HEK293 cells, while resulting in altered degradation in major neurons. Overall, our knowledge hyperlinks ALS/FTD-causing mutations in CCNF to converging pathological options of ALS/FTD and supplies a hyperlink between faulty protein degradation programs and the pathological accumulation of a protein concerned in RNA processing and metabolism. Once generated in vivo, trans-3MGC acid is proposed to isomerize through a mechanism involving π electron delocalization with formation of a resonance construction that allows bond rotation.