3-Methylglutaconic (3MGC) aciduria is a typical phenotypic function of a rising quantity of inborn errors of metabolism. “Primary” 3MGC aciduria is attributable to deficiencies in leucine pathway enzymes whereas “secondary” 3MGC aciduria outcomes from inborn errors of metabolism that impression mitochondrial vitality manufacturing. The metabolic precursor of 3MGC acid is trans-3MGC CoA, an intermediate within the leucine catabolism pathway. Gas chromatography-mass spectrometry (GC-MS) evaluation of commercially out there trans-3MGC acid yielded a combination of cis and trans isomers whereas 1H-NMR spectroscopy of trans-3MGC acid at 25°C supplied no proof for the cis isomer.
When trans-3MGC acid was incubated beneath circumstances used for pattern derivatization previous to GC-MS (however with no trimethylsilane added), 1H-NMR spectroscopy supplied proof of trans to cis isomerization. Incubation of trans-3MGC acid at 37°C resulted in time-dependent isomerization to cis-3MGC acid. Cis-3MGC acid behaved in the same method besides that, beneath equivalent incubation circumstances, much less isomerization occurred. In settlement with these experimental outcomes, molecular modeling research supplied proof that the vitality minimized construction of cis-3MGC acid is four kJ/mol extra secure than that for trans-3MGC acid.
The knowledge introduced are according to the incidence of each diastereomers in urine samples of topics with 3MGC aciduria. Quantification of iron is a crucial step to evaluate the iron burden in sufferers affected by iron overload illnesses, in addition to super worth in understanding the underlying function of iron within the pathophysiology of these illnesses. Current iron willpower of complete or labile iron, requires in depth pattern dealing with and specialised devices, while being time consuming and laborious. Moreover, there’s minimal to no overlap between complete iron and labile iron quantification methodologies-i.e. requiring totally separate protocols, strategies and devices. Herein, we report a unified-ferene (u-ferene) assay that allows a 2-in-1 quantification of each labile and complete iron from the identical preparation of a organic specimen.
MANTI: Automated Annotation of Protein N-Termini for Rapid Interpretation of N-Terminome Data Sets
Site-specific proteolytic processing is a crucial, irreversible post-translational protein modification with implications in lots of illnesses. Enrichment of protein N-terminal peptides adopted by mass spectrometry-based identification and quantification allows proteome-wide characterization of proteolytic processes and protease substrates however is challenged by the shortage of particular annotation instruments. A typical downside is, for instance, ambiguous matches of recognized peptides to a number of protein entries within the databases used for identification.
We developed MaxQuant Advanced N-termini Interpreter (MANTI), a standalone Perl software program with an optionally available graphical consumer interface that validates and annotates N-terminal peptides recognized by database searches with the favored MaxQuant software program bundle by integrating data from a number of knowledge sources. MANTI makes use of numerous annotation data in a multistep determination course of to assign a conservative most well-liked protein entry for every N-terminal peptide, enabling automated classification in line with the doubtless origin and determines important adjustments in N-terminal peptide abundance. Auxiliary R scripts included within the software program bundle summarize and visualize key facets of the information.
To showcase the utility of MANTI, we generated two large-scale TAILS N-terminome knowledge units from two completely different animal fashions of chemically and genetically induced kidney illness, puromycin adenonucleoside-treated rats (PAN), and heterozygous Wilms Tumor protein 1 mice (WT1). MANTI enabled fast validation and autonomous annotation of >10 000 recognized terminal peptides, revealing novel proteolytic proteoforms in 905 and 644 proteins, respectively. Quantitative evaluation indicated that proteolytic actions with related sequence specificity are concerned within the pathogenesis of kidney harm and proteinuria in each fashions, whereas coagulation processes and complement activation have been particularly induced after chemical harm.
ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ
Previously, we recognized missense mutations in CCNF which can be causative of familial and sporadic amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Hallmark options of these illnesses embody the build-up of insoluble protein aggregates in addition to the mislocalisation of proteins reminiscent of TDP-43. In latest years, the dysregulation of SFPQ has additionally emerged as a pathological hallmark of ALS/FTD. CCNF encodes for the protein cyclin F, a substrate recognition part of an E3-ubiquitin ligase. We have beforehand proven that ALS/FTD-linked mutations in CCNF trigger disruptions to general protein homeostasis that results in a build-up of Ok48-linked ubiquitylated proteins in addition to defects in autophagic equipment.
To examine additional processes that could be affected by cyclin F, we used a protein-proximity ligation methodology, often known as BioID, customary immunoprecipitations and mass spectrometry (MS) to establish novel interplay companions of cyclin F and infer additional course of that could be affected by the ALS/FTD-causing mutation. Results display that cyclin F intently associates with proteins concerned with RNA metabolism in addition to a quantity of RNA binding proteins beforehand linked to ALS/FTD, together with splicing issue proline and glutamine wealthy (SFPQ).
HSC70 Interacting Protein HIP (ST13) Rabbit Polyclonal Antibody |
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| E10G30095 | EnoGene | 100 μl | EUR 275 |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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Rabbit Polyclonal antibody to HHIP (hedgehog interacting protein) |
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| TA308452 | Origene Technologies GmbH | 100 µl | Ask for price |
Rabbit anti-human TRAF interacting protein polyclonal Antibody |
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| MBS713038-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human TRAF interacting protein polyclonal Antibody |
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| MBS713038-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human toll interacting protein polyclonal Antibody |
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| MBS713252-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human toll interacting protein polyclonal Antibody |
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| MBS713252-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human MLX interacting protein polyclonal Antibody |
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| MBS713268-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human MLX interacting protein polyclonal Antibody |
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| MBS713268-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human MLF1 interacting protein polyclonal Antibody |
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| MBS711757-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human MLF1 interacting protein polyclonal Antibody |
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| MBS711757-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human ATR interacting protein polyclonal Antibody |
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| MBS712023-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human ATR interacting protein polyclonal Antibody |
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| MBS712023-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human CDKN2A interacting protein polyclonal Antibody |
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| MBS716253-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human CDKN2A interacting protein polyclonal Antibody |
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| MBS716253-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human PSMC3 interacting protein polyclonal Antibody |
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| MBS710863-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human PSMC3 interacting protein polyclonal Antibody |
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| MBS710863-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human SEC23 interacting protein polyclonal Antibody |
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| MBS710915-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human SEC23 interacting protein polyclonal Antibody |
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| MBS710915-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human APAF1 interacting protein polyclonal Antibody |
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| MBS713450-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human APAF1 interacting protein polyclonal Antibody |
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| MBS713450-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human hedgehog interacting protein polyclonal Antibody |
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| MBS716208-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human hedgehog interacting protein polyclonal Antibody |
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| MBS716208-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human TIMELESS interacting protein polyclonal Antibody |
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| MBS712796-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human TIMELESS interacting protein polyclonal Antibody |
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| MBS712796-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human HIRA interacting protein 3 polyclonal Antibody |
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| MBS714732-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human HIRA interacting protein 3 polyclonal Antibody |
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| MBS714732-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human DAZ interacting protein 1 polyclonal Antibody |
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| MBS711006-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human DAZ interacting protein 1 polyclonal Antibody |
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| MBS711006-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human PAK1 interacting protein 1 polyclonal Antibody |
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| MBS713007-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human PAK1 interacting protein 1 polyclonal Antibody |
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| MBS713007-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human Opa interacting protein 5 polyclonal Antibody |
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| MBS712606-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human Opa interacting protein 5 polyclonal Antibody |
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| MBS712606-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Smad Interacting Protein 1 (ZEB2) rabbit polyclonal antibody, Aff - Purified |
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| AP01369PU-N | Origene Technologies GmbH | 100 µg | Ask for price |
Rabbit anti-human RAB3A interacting protein (rabin3) polyclonal Antibody |
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| MBS713430-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human RAB3A interacting protein (rabin3) polyclonal Antibody |
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| MBS713430-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human TNFAIP3 interacting protein 1 polyclonal Antibody |
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| MBS714790-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human TNFAIP3 interacting protein 1 polyclonal Antibody |
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| MBS714790-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human TNFAIP3 interacting protein 2 polyclonal Antibody |
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| MBS711234-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human TNFAIP3 interacting protein 2 polyclonal Antibody |
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| MBS711234-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human MLX interacting protein-like polyclonal Antibody |
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| MBS711306-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human MLX interacting protein-like polyclonal Antibody |
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| MBS711306-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human huntingtin interacting protein 1 polyclonal Antibody |
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| MBS713636-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human huntingtin interacting protein 1 polyclonal Antibody |
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| MBS713636-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit polyclonal antibody to EPM2AIP1 (EPM2A (laforin) interacting protein 1) |
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| TA308270 | Origene Technologies GmbH | 100 µl | Ask for price |
Rabbit Polyclonal antibody to CYFIP2 (cytoplasmic FMR1 interacting protein 2) |
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| TA307895 | Origene Technologies GmbH | 100 µl | Ask for price |
Rabbit anti-human Kv channel interacting protein 1 polyclonal Antibody |
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| MBS716692-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human Kv channel interacting protein 1 polyclonal Antibody |
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| MBS716692-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human Kv channel interacting protein 4 polyclonal Antibody |
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| MBS719141-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human Kv channel interacting protein 4 polyclonal Antibody |
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| MBS719141-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Smad Interacting Protein 1 (ZEB2) (C-term) rabbit polyclonal antibody, Purified |
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| AP31202PU-N | Origene Technologies GmbH | 50 µg | Ask for price |
Smad Interacting Protein 1 (ZEB2) (N-term) rabbit polyclonal antibody, Purified |
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| AP31272PU-N | Origene Technologies GmbH | 50 µl | Ask for price |
Rabbit polyclonal antibody to NOSIP (nitric oxide synthase interacting protein) |
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| TA308380 | Origene Technologies GmbH | 100 µl | Ask for price |
Rpa Interacting Protein Antibody |
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| 20-abx115340 | Abbexa |
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RPA Interacting Protein Antibody |
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| 24482 | SAB | 100ul | EUR 479 |
RPA Interacting Protein Antibody |
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| 24482-100ul | SAB | 100ul | EUR 468 |
RPA Interacting Protein Antibody |
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| 24483 | SAB | 100ul | EUR 479 |
RPA Interacting Protein Antibody |
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| 24483-100ul | SAB | 100ul | EUR 468 |
RPA Interacting Protein Antibody |
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| 4013-002mg | ProSci | 0.02 mg | EUR 206.18 |
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Description: RPA Interacting Protein Antibody: Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism. |
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RPA Interacting Protein Antibody |
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| 4013-01mg | ProSci | 0.1 mg | EUR 523.7 |
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Description: RPA Interacting Protein Antibody: Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism. |
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RPA Interacting Protein Antibody |
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| 4015-002mg | ProSci | 0.02 mg | EUR 206.18 |
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Description: RPA Interacting Protein Antibody: Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism. |
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RPA Interacting Protein Antibody |
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| 4015-01mg | ProSci | 0.1 mg | EUR 523.7 |
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Description: RPA Interacting Protein Antibody: Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism. |
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Rpa Interacting Protein Antibody |
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| abx115340-100l | Abbexa | 100 µl | EUR 612.5 |
RPA Interacting Protein Antibody |
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| MBS9401297-01mL | MyBiosource | 0.1mL | EUR 495 |
RPA Interacting Protein Antibody |
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| MBS9401297-5x01mL | MyBiosource | 5x0.1mL | EUR 2075 |
RPA Interacting Protein Antibody |
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| MBS9410979-01mL | MyBiosource | 0.1mL | EUR 495 |
RPA Interacting Protein Antibody |
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| MBS9410979-5x01mL | MyBiosource | 5x0.1mL | EUR 2075 |
RPA Interacting Protein Antibody |
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| MBS150791-01mg | MyBiosource | 0.1mg | EUR 445 |
RPA Interacting Protein Antibody |
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| MBS150791-5x01mg | MyBiosource | 5x0.1mg | EUR 1965 |
RPA Interacting Protein Antibody |
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| MBS150388-01mg | MyBiosource | 0.1mg | EUR 445 |
RPA Interacting Protein Antibody |
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| MBS150388-5x01mg | MyBiosource | 5x0.1mg | EUR 1965 |
MLX interacting protein (MLXIP) (N-term) rabbit polyclonal antibody, Aff - Purified |
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| AP52708PU-N | Origene Technologies GmbH | 400 µl | Ask for price |
TNFAIP3 Interacting Protein 2 (TNIP2) Rabbit anti-Human Polyclonal Antibody |
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| GWB-78905D | GenWay Biotech | 0.05 mg | Ask for price |
Rabbit anti-human BRCA2 and CDKN1A interacting protein polyclonal Antibody |
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| MBS711064-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human BRCA2 and CDKN1A interacting protein polyclonal Antibody |
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| MBS711064-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human Smad nuclear interacting protein 1 polyclonal Antibody |
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| MBS711000-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human Smad nuclear interacting protein 1 polyclonal Antibody |
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| MBS711000-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit Polyclonal antibody to ARA9 (aryl hydrocarbon receptor interacting protein) |
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| TA308832 | Origene Technologies GmbH | 100 µl | Ask for price |
Rabbit polyclonal antibody to TOK-1 alpha (BRCA2 and CDKN1A interacting protein) |
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| TA308557 | Origene Technologies GmbH | 100 µl | Ask for price |
Rabbit anti-human poly(A) binding protein interacting protein 1 polyclonal Antibody |
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| MBS716840-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human poly(A) binding protein interacting protein 1 polyclonal Antibody |
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| MBS716840-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human Werner helicase interacting protein 1 polyclonal Antibody |
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| MBS713748-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human Werner helicase interacting protein 1 polyclonal Antibody |
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| MBS713748-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human RAB3A interacting protein (rabin3)-like 1 polyclonal Antibody |
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| MBS716330-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human RAB3A interacting protein (rabin3)-like 1 polyclonal Antibody |
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| MBS716330-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Smad Interacting Protein 1 (ZEB2) (C-term) rabbit polyclonal antibody, Aff - Purified |
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| AP54642PU-N | Origene Technologies GmbH | 400 µl | Ask for price |
Toll Interacting Protein (TOLLIP) Rabbit anti-Human Polyclonal (Internal) Antibody |
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| GWB-A41300 | GenWay Biotech | 0.05 mg | Ask for price |
Rabbit anti-human NCK interacting protein with SH3 domain polyclonal Antibody |
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| MBS716137-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human NCK interacting protein with SH3 domain polyclonal Antibody |
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| MBS716137-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human cytoplasmic FMR1 interacting protein 2 polyclonal Antibody |
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| MBS714881-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human cytoplasmic FMR1 interacting protein 2 polyclonal Antibody |
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| MBS714881-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human nuclear receptor interacting protein 2 polyclonal Antibody |
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| MBS716708-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human nuclear receptor interacting protein 2 polyclonal Antibody |
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| MBS716708-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
MLF1 Interacting Protein (MLF1IP) Rabbit anti-Human Polyclonal (pThr78) Antibody |
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| GWB-8D8859 | GenWay Biotech | 0.05 mg | Ask for price |
MLF1 Interacting Protein (MLF1IP) Rabbit anti-Human Polyclonal (pThr78) Antibody |
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| GWB-C28093 | GenWay Biotech | 0.05 mg | Ask for price |
Rabbit anti-human huntingtin interacting protein 1 related polyclonal Antibody |
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| MBS714253-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human huntingtin interacting protein 1 related polyclonal Antibody |
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| MBS714253-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human myosin phosphatase Rho interacting protein polyclonal Antibody |
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| MBS713196-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human myosin phosphatase Rho interacting protein polyclonal Antibody |
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| MBS713196-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human protein interacting with PRKCA 1 polyclonal Antibody |
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| MBS713902-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human protein interacting with PRKCA 1 polyclonal Antibody |
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| MBS713902-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human RAB11 family interacting protein 5 (class I) polyclonal Antibody |
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| MBS711724-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human RAB11 family interacting protein 5 (class I) polyclonal Antibody |
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| MBS711724-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human RAB11 family interacting protein 2 (class I) polyclonal Antibody |
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| MBS711769-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human RAB11 family interacting protein 2 (class I) polyclonal Antibody |
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| MBS711769-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human cannabinoid receptor interacting protein 1 polyclonal Antibody |
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| MBS714232-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human cannabinoid receptor interacting protein 1 polyclonal Antibody |
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| MBS714232-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human programmed cell death 6 interacting protein polyclonal Antibody |
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| MBS716795-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human programmed cell death 6 interacting protein polyclonal Antibody |
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| MBS716795-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human Kv channel interacting protein 3, calsenilin polyclonal Antibody |
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| MBS710085-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human Kv channel interacting protein 3, calsenilin polyclonal Antibody |
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| MBS710085-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human pleckstrin homology domain interacting protein polyclonal Antibody |
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| MBS711530-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human pleckstrin homology domain interacting protein polyclonal Antibody |
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| MBS711530-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit Polyclonal antibody to PPFIBP2 (PTPRF interacting protein, binding protein 2 (liprin beta 2)) |
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| TA308142 | Origene Technologies GmbH | 100 µl | Ask for price |
Rabbit anti-human WAS/WASL interacting protein family, member 2 polyclonal Antibody |
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| MBS711312-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human WAS/WASL interacting protein family, member 2 polyclonal Antibody |
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| MBS711312-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human serine/threonine kinase 11 interacting protein polyclonal Antibody |
|||
| MBS716784-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human serine/threonine kinase 11 interacting protein polyclonal Antibody |
|||
| MBS716784-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human survival of motor neuron protein interacting protein 1 polyclonal Antibody |
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| MBS713390-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human survival of motor neuron protein interacting protein 1 polyclonal Antibody |
|||
| MBS713390-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human BCL2/adenovirus E1B 19kDa interacting protein 1 polyclonal Antibody |
|||
| MBS716732-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human BCL2/adenovirus E1B 19kDa interacting protein 1 polyclonal Antibody |
|||
| MBS716732-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Toll Interacting Protein (TOLLIP) Rabbit anti-Human Polyclonal (C-Terminus) Antibody |
|||
| GWB-FEF02F | GenWay Biotech | 0.05 mg | Ask for price |
Rabbit anti-human ADP-ribosylation factor interacting protein 2 polyclonal Antibody |
|||
| MBS716659-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human ADP-ribosylation factor interacting protein 2 polyclonal Antibody |
|||
| MBS716659-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human myosin regulatory light chain interacting protein polyclonal Antibody |
|||
| MBS716823-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human myosin regulatory light chain interacting protein polyclonal Antibody |
|||
| MBS716823-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human ADP-ribosylation factor interacting protein 1 polyclonal Antibody |
|||
| MBS711324-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human ADP-ribosylation factor interacting protein 1 polyclonal Antibody |
|||
| MBS711324-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit anti-human phytanoyl-CoA 2-hydroxylase interacting protein polyclonal Antibody |
|||
| MBS712399-01mL | MyBiosource | 0.1mL | EUR 485 |
Rabbit anti-human phytanoyl-CoA 2-hydroxylase interacting protein polyclonal Antibody |
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| MBS712399-5x01mL | MyBiosource | 5x0.1mL | EUR 2175 |
Rabbit Polyclonal antibody to VCPIP1 (valosin containing protein (p97)/p47 complex interacting protein 1) |
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| TA309036 | Origene Technologies GmbH | 100 µl | Ask for price |
Rabbit anti-human PTPRF interacting protein, binding protein 1 (liprin beta 1) polyclonal Antibody |
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| MBS714607-01mL | MyBiosource | 0.1mL | EUR 485 |
Notably, the overexpression of cyclin F(S621G) led to the aggregation and altered subcellular distribution of SFPQ in HEK293 cells, while resulting in altered degradation in major neurons. Overall, our knowledge hyperlinks ALS/FTD-causing mutations in CCNF to converging pathological options of ALS/FTD and supplies a hyperlink between faulty protein degradation programs and the pathological accumulation of a protein concerned in RNA processing and metabolism. Once generated in vivo, trans-3MGC acid is proposed to isomerize through a mechanism involving π electron delocalization with formation of a resonance construction that allows bond rotation.