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Design of Abiological Digital Poly(phosphodiester)s

Design of Abiological Digital Poly(phosphodiester)s

ConspectusIn organic techniques, the storage and switch of genetic data depend on sequence-controlled nucleic acids reminiscent of DNA and RNA. It has been realized for fairly a while that this property isn’t solely essential for all times however is also very helpful in human purposes. For occasion, DNA has been actively investigated as a digital storage medium over the previous decade. Indeed, the “hard-disk of life” is an apparent alternative and a extremely optimized materials for storing knowledge. Through a long time of nucleic acids analysis, technological instruments for parallel synthesis and sequencing of DNA have been available.

Consequently, it has already been demonstrated that differing types of paperwork (e.g., texts, photographs, movies, and industrial knowledge) might be saved in chemically synthesized DNA libraries. However, DNA is topic to organic constraints, and its molecular construction can’t be simply diverse to match technological wants. In reality, DNA isn’t the one macromolecule that permits knowledge storage. In current years, it has been demonstrated that all kinds of artificial polymers will also be used for such a function. Indeed, fashionable polymer synthesis permits the preparation of artificial macromolecules with exactly managed monomer sequences. Altogether, a couple of dozens of artificial digital polymers have already been described, and lots of extra might be foreseen.

Among them, sequence-defined poly(phosphodiester)s are one of probably the most promising choices. These polymers are ready by stepwise phosphoramidite chemistry like chemically synthesized oligonucleotides. However, they’re constructed with non-natural constructing blocks and subsequently share nearly no structural traits with nucleic acids, besides phosphate repeat items. Still, they include readable digital messages that may be deciphered by nanopore sequencing or mass spectrometry sequencing. In this Account, we describe our current analysis efforts in synthesizing and sequencing optimum abiological digital poly(phosphodiester)s. A significant benefit of these polymers over DNA is that their molecular construction can simply be diverse to tune their properties.

During the final 5 years, we have now engineered the molecular construction of these polymers to regulate essential parameters such because the storage density, storage capability, erasability, and readability. Consequently, high-capacity PPDE chains, containing tons of of bits per chains, can now be synthesized and effectively sequenced utilizing a routine mass spectrometer. Furthermore, sequencing knowledge might be routinely decrypted with the assistance of decoding software program. This new sort of coded matter will also be edited utilizing sensible bodily triggers reminiscent of mild and arranged in area by programmed self-assembly. All of these current enhancements are summarized and mentioned herein.

Identification of Protein Direct Interactome with Genetic Code Expansion and Search Engine OpenUaa

Protein crosslinks happen endogenously reminiscent of modifications by ubiquitin-like proteins for signaling, or exogenously by way of genetically encoded chemical crosslinkers (GECX) for finding out elusive protein-protein interactions. However, it stays difficult to establish these protein crosslinks effectively on the proteomic scale. Herein, software program OpenUaa is developed for figuring out protein crosslinks generated by genetically encoded unnatural amino acids and endogenous protein conjugation. OpenUaa options inclusive and open search functionality, dramatically enhancing identification sensitivity and protection.

Integrating GECX with OpenUaa, the direct interactome of thioredoxin is recognized in Escherichia coli cells, yielding 289 crosslinked peptides and similar to 205 direct binding protein of thioredoxin. These recognized direct binders present proof for thioredoxin’s regulation of redox state and mitochondria power metabolism. When figuring out endogenous conjugation of small ubiquitin-like modifier (SUMO), OpenUaa additionally markedly improves protection of SUMOylated peptides by ≈92%, revealing new SUMO targets. GECX-OpenUaa will allow environment friendly identification of direct interactomes of varied proteins in dwell cells.

Synaptic transmission depends on the continuous exocytosis and recycling of synaptic vesicles. Aged vesicle proteins are prevented from recycling and are ultimately degraded. This implies that lively synapses would lose vesicles and vesicle-associated proteins over time, except the provision correlates to exercise, to steadiness the losses. To check this speculation, we first mannequin the quantitative relation between presynaptic spike price and vesicle turnover. The mannequin predicts that the vesicle provide wants to extend with the spike price. To observe up this prediction, we measure protein turnover in particular person synapses of cultured hippocampal neurons by combining nanoscale secondary ion mass spectrometry (nanoSIMS) and fluorescence microscopy.

Design of Abiological Digital Poly(phosphodiester)s

Fast Nanoliter-Scale Cell Assays Using Droplet Microarray-Mass Spectrometry Imaging

In pharmaceutical analysis and growth, cell-based assays are primarily used with readout that depend on fluorescence-based and different label-dependent methods for evaluation of totally different mobile processes. Superhydrophobic-hydrophilic droplet microarrays (DMA) and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) have lately emerged as key applied sciences for miniaturized high-throughput cell assays and for label-free molecular high-content drug profiling, respectively. Here, nanoliter-scale cell assays are built-in on DMAs with MALDI-MS imaging (MALDI-MSI) approaches to a droplet microarray-mass spectrometry imaging (DMA-MSI) platform.

Pancreas/duodenum homeobox protein 1

AP79443 1mg
EUR 2640

Pancreas/duodenum homeobox protein 1

AP86328 1mg
EUR 2640

Pancreas/duodenum homeobox protein 1

AP86604 1mg
EUR 2640

Pancreas Duodenum Homeobox-1 (PDX-1) Antibody

abx137204-01mg 0.1 mg
EUR 225

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

20-abx126342
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  • Ask for price
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

20-abx127002
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  • Ask for price
  • 100 ul
  • 200 ul

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx033651-400ul 400 ul
EUR 627.6

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx033651-80l 80 µl
EUR 343.2

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx015963-100ug 100 ug
EUR 493.2

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx015964-100ug 100 ug
EUR 493.2

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

20-abx002213
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  • Ask for price
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  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

20-abx242867
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  • Ask for price
  • 150 ul
  • 50 ul

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

20-abx213983
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  • Ask for price
  • 100 ul
  • 50 ul

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

20-abx327762
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  • Ask for price
  • 100 ug
  • 50 ug

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

20-abx241830
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  • Ask for price
  • 100 ul
  • 50 ul

PDX1 Antibody / Pancreas/duodenum homeobox protein 1

RQ5749 100 ug
EUR 356.15
Description: PDX1 (pancreatic and duodenal homeobox 1), also known as insulin promoter factor 1, is a transcription factor in the ParaHox gene cluster. The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

abx213983-100l 100 µl
EUR 250

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx033651-100g 100 µg
EUR 250

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx015963-1mg 1 mg
EUR 362.5

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx015964-1mg 1 mg
EUR 362.5

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

abx242867-96tests 96 tests
EUR 612.5

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

abx241830-96tests 96 tests
EUR 250

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx126342-100l 100 µl
EUR 175

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx126342-1ml 1 ml
EUR 400

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx126342-200l 200 µl
EUR 275

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx215738-100tests 100 tests Ask for price

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx215738-20tests 20 tests
EUR 350

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx215738-50tests 50 tests Ask for price

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

abx327762-100g 100 µg
EUR 250

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

abx327762-50g 50 µg
EUR 187.5

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx002213-100l 100 µl
EUR 400

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx002213-20l 20 µl
EUR 175

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx002213-50l 50 µl
EUR 275

PDX1 Antibody / Pancreas/duodenum homeobox protein 1

V9260-100UG 100ug
EUR 349.3
Description: Pancreatic duodenal homeobox-1 protein (PDX-1), also designated Insulin promoter factor (IPF1), Insulin upstream factor 1 (IUF1), somatostatin transactivating factor-1 (STF-1) and glucose-sensitive factor (GSF), is a 282 amino acid homeodomain-containing transcription factor present in pancreatic cells. PDX-1 binds to the sequence C(C/T) and can heterodimerize with PBX. PDX-1 is phosphorylated by the SAPK2 pathway under high glucose concentrations. Mutations in the PDX-1 gene can cause maturity-onset diabetes of the young and pancreatic agenesis. The gene which encodes PDX-1 maps to human chromosome 13q12.2.

PDX1 Antibody / Pancreas/duodenum homeobox protein 1

V9260-20UG 20ug
EUR 153.3
Description: Pancreatic duodenal homeobox-1 protein (PDX-1), also designated Insulin promoter factor (IPF1), Insulin upstream factor 1 (IUF1), somatostatin transactivating factor-1 (STF-1) and glucose-sensitive factor (GSF), is a 282 amino acid homeodomain-containing transcription factor present in pancreatic cells. PDX-1 binds to the sequence C(C/T) and can heterodimerize with PBX. PDX-1 is phosphorylated by the SAPK2 pathway under high glucose concentrations. Mutations in the PDX-1 gene can cause maturity-onset diabetes of the young and pancreatic agenesis. The gene which encodes PDX-1 maps to human chromosome 13q12.2.

PDX1 Antibody / Pancreas/duodenum homeobox protein 1

V9260SAF-100UG 100ug
EUR 349.3
Description: Pancreatic duodenal homeobox-1 protein (PDX-1), also designated Insulin promoter factor (IPF1), Insulin upstream factor 1 (IUF1), somatostatin transactivating factor-1 (STF-1) and glucose-sensitive factor (GSF), is a 282 amino acid homeodomain-containing transcription factor present in pancreatic cells. PDX-1 binds to the sequence C(C/T) and can heterodimerize with PBX. PDX-1 is phosphorylated by the SAPK2 pathway under high glucose concentrations. Mutations in the PDX-1 gene can cause maturity-onset diabetes of the young and pancreatic agenesis. The gene which encodes PDX-1 maps to human chromosome 13q12.2.

Rat Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS2881770-10x96StripWells 10x96-Strip-Wells
EUR 4630

Rat Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS2881770-48StripWells 48-Strip-Wells
EUR 440

Rat Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS2881770-5x96StripWells 5x96-Strip-Wells
EUR 2480

Rat Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS2881770-96StripWells 96-Strip-Wells
EUR 580

Human Pancreas/duodenum homeobox protein 1 ELISA Kit

EK4887 96 tests
EUR 659

Human Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS765647-10x96StripWells 10x96-Strip-Wells
EUR 3900

Human Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS765647-48StripWells 48-Strip-Wells
EUR 340

Human Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS765647-5x96StripWells 5x96-Strip-Wells
EUR 2045

Human Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS765647-96StripWells 96-Strip-Wells
EUR 455

Human Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS289476-10x96StripWells 10x96-Strip-Wells
EUR 4630

Human Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS289476-48StripWells 48-Strip-Wells
EUR 440

Human Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS289476-5x96StripWells 5x96-Strip-Wells
EUR 2480

Human Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS289476-96StripWells 96-Strip-Wells
EUR 580

Mouse Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS2887091-10x96StripWells 10x96-Strip-Wells
EUR 4630

Mouse Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS2887091-48StripWells 48-Strip-Wells
EUR 440

Mouse Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS2887091-5x96StripWells 5x96-Strip-Wells
EUR 2480

Mouse Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS2887091-96StripWells 96-Strip-Wells
EUR 580

Human Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS9428713-5x96Tests 5x96Tests
EUR 3065

Human Pancreas/duodenum homeobox protein 1 ELISA Kit

MBS9428713-96Tests 96Tests
EUR 670

Recombinant Rat Pancreas/duodenum homeobox protein 1 (Pdx1)

MBS962930-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1160

Recombinant Rat Pancreas/duodenum homeobox protein 1 (Pdx1)

MBS962930-002mgEColi 0.02mg(E-Coli)
EUR 800

Recombinant Rat Pancreas/duodenum homeobox protein 1 (Pdx1)

MBS962930-002mgYeast 0.02mg(Yeast)
EUR 950

Recombinant Rat Pancreas/duodenum homeobox protein 1 (Pdx1)

MBS962930-01mgEColi 0.1mg(E-Coli)
EUR 965

Recombinant Rat Pancreas/duodenum homeobox protein 1 (Pdx1)

MBS962930-01mgYeast 0.1mg(Yeast)
EUR 1115

Rat Pancreas/duodenum homeobox protein 1 (PDX1) ELISA Kit

abx520946-96tests 96 tests
EUR 801.6

Rat Pdx1/ Pancreas/duodenum homeobox protein 1 ELISA Kit

E0744Ra 1 Kit
EUR 557
Description: Ipf1,Insulin promoter factor 1,Islet/duodenum homeobox 1,Somatostatin-transactivating factor 1,IPF-1,IDX-1,STF-1

Rat Pancreas/duodenum homeobox protein 1 (PDX1) ELISA Kit

RK14574 96T
EUR 280

Rat Pdx1 / Pancreas/duodenum homeobox protein 1 ELISA Kit

E9043r 96T
EUR 796

Rat Pancreas/duodenum homeobox protein 1, PDX1 ELISA Kit

MBS9330466-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat Pancreas/duodenum homeobox protein 1, PDX1 ELISA Kit

MBS9330466-48StripWells 48-Strip-Wells
EUR 550

Rat Pancreas/duodenum homeobox protein 1, PDX1 ELISA Kit

MBS9330466-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat Pancreas/duodenum homeobox protein 1, PDX1 ELISA Kit

MBS9330466-96StripWells 96-Strip-Wells
EUR 765

Cat Pancreas/Duodenum Homeobox Protein 1 (PDX1) ELISA Kit

MBS9352695-INQUIRE INQUIRE Ask for price

Fish Pancreas;Duodenum Homeobox Protein 1,PDX1 ELISA KIT

E0235FI-1096T 10*96T
EUR 4482

Fish Pancreas;Duodenum Homeobox Protein 1,PDX1 ELISA KIT

E0235FI-48wells 48 wells
EUR 360

Fish Pancreas;Duodenum Homeobox Protein 1,PDX1 ELISA KIT

E0235FI-596T 5*96T
EUR 2241

Fish Pancreas;Duodenum Homeobox Protein 1,PDX1 ELISA KIT

E0235FI-96wells 96 wells
EUR 498

Duck Pancreas/Duodenum Homeobox Protein 1 (PDX1) ELISA Kit

MBS9367917-INQUIRE INQUIRE Ask for price

Cavy Pancreas/Duodenum Homeobox Protein 1 (PDX1) ELISA Kit

MBS9346580-INQUIRE INQUIRE Ask for price

Goat Pancreas/Duodenum Homeobox Protein 1 (PDX1) ELISA Kit

MBS9355661-INQUIRE INQUIRE Ask for price

Fish Pancreas/Duodenum Homeobox Protein 1, PDX1 ELISA Kit

MBS1607473-10x96StripWells 10x96-Strip-Wells
EUR 4470

Fish Pancreas/Duodenum Homeobox Protein 1, PDX1 ELISA Kit

MBS1607473-48StripWells 48-Strip-Wells
EUR 415

Fish Pancreas/Duodenum Homeobox Protein 1, PDX1 ELISA Kit

MBS1607473-5x96StripWells 5x96-Strip-Wells
EUR 2270

Fish Pancreas/Duodenum Homeobox Protein 1, PDX1 ELISA Kit

MBS1607473-96StripWells 96-Strip-Wells
EUR 540

Recombinant Human Pancreas/duodenum homeobox protein 1 (PDX1)

MBS956388-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1160

Recombinant Human Pancreas/duodenum homeobox protein 1 (PDX1)

MBS956388-002mgEColi 0.02mg(E-Coli)
EUR 800

Recombinant Human Pancreas/duodenum homeobox protein 1 (PDX1)

MBS956388-002mgYeast 0.02mg(Yeast)
EUR 950

Recombinant Human Pancreas/duodenum homeobox protein 1 (PDX1)

MBS956388-01mgEColi 0.1mg(E-Coli)
EUR 965

Recombinant Human Pancreas/duodenum homeobox protein 1 (PDX1)

MBS956388-01mgYeast 0.1mg(Yeast)
EUR 1115

Recombinant Mouse Pancreas/duodenum homeobox protein 1 (Pdx1)

MBS966387-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1165

Recombinant Mouse Pancreas/duodenum homeobox protein 1 (Pdx1)

MBS966387-002mgEColi 0.02mg(E-Coli)
EUR 805

Recombinant Mouse Pancreas/duodenum homeobox protein 1 (Pdx1)

MBS966387-002mgYeast 0.02mg(Yeast)
EUR 955

Recombinant Mouse Pancreas/duodenum homeobox protein 1 (Pdx1)

MBS966387-01mgEColi 0.1mg(E-Coli)
EUR 965

Recombinant Mouse Pancreas/duodenum homeobox protein 1 (Pdx1)

MBS966387-01mgYeast 0.1mg(Yeast)
EUR 1115

Human Pancreas/duodenum homeobox protein 1 (PDX1) ELISA Kit

abx251794-96tests 96 tests
EUR 801.6

Mouse Pancreas/duodenum homeobox protein 1 (PDX1) ELISA Kit

abx520945-96tests 96 tests
EUR 801.6

Human PDX1/ Pancreas/duodenum homeobox protein 1 ELISA Kit

E1899Hu 1 Kit
EUR 515
Description: IPF1,STF1,Glucose-sensitive factor,Insulin promoter factor 1,Insulin upstream factor 1,Islet/duodenum homeobox-1,Somatostatin-transactivating factor 1,GSF,IPF-1,IUF-1,IDX-1,STF-1

Human PDX1(Pancreas/duodenum homeobox protein 1) ELISA Kit

EH2431 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human PDX1(Pancreas/duodenum homeobox protein 1) ELISA Kit

EKF58999-48T 48T
EUR 396.9

Human PDX1(Pancreas/duodenum homeobox protein 1) ELISA Kit

EKF58999-5x96T 5x96T
EUR 2693.25

Human PDX1(Pancreas/duodenum homeobox protein 1) ELISA Kit

EKF58999-96T 96T
EUR 567

Sheep Pancreas/duodenum homeobox protein 1 (PDX1) ELISA Kit

AE64478SH-48Tests 48 Tests
EUR 325
Description: Sheep (Ovis aries)

Sheep Pancreas/duodenum homeobox protein 1 (PDX1) ELISA Kit

AE64478SH-96Tests 96 Tests
EUR 610
Description: Sheep (Ovis aries)

Human Pancreas/duodenum homeobox protein 1, PDX1 ELISA KIT

ELI-15305h 96tests
EUR 696

Mouse Pancreas/duodenum homeobox protein 1, Pdx1 ELISA KIT

ELI-16116m 96tests
EUR 736

Human Pancreas;Duodenum Homeobox Protein 1,PDX1 ELISA KIT

E6802Hu-1096T 10*96T
EUR 4122

Human Pancreas;Duodenum Homeobox Protein 1,PDX1 ELISA KIT

E6802Hu-48wells 48 wells
EUR 300

Human Pancreas;Duodenum Homeobox Protein 1,PDX1 ELISA KIT

E6802Hu-596T 5*96T
EUR 2061

Human Pancreas;Duodenum Homeobox Protein 1,PDX1 ELISA KIT

E6802Hu-96wells 96 wells
EUR 458

Human Pancreas/duodenum homeobox protein 1 (PDX1) ELISA Kit

RK11628 96T
EUR 280

Human PDX1 / Pancreas/duodenum homeobox protein 1 ELISA Kit

E9043h 96T
EUR 736

Mouse Pdx1 / Pancreas/duodenum homeobox protein 1 ELISA Kit

E9043m 96T
EUR 776

Human Pancreas/duodenum homeobox protein 1 (PDX1) ELISA Kit

AE28112HU-48T 48T
EUR 325
Description: Human (Homo sapiens)

Human Pancreas/duodenum homeobox protein 1 (PDX1) ELISA Kit

AE28112HU-96T 96T
EUR 610
Description: Human (Homo sapiens)

Horse Pancreas/Duodenum Homeobox Protein 1 (PDX1) ELISA Kit

MBS9362484-10x96StripWells 10x96-Strip-Wells
EUR 6725

Horse Pancreas/Duodenum Homeobox Protein 1 (PDX1) ELISA Kit

MBS9362484-48StripWells 48-Strip-Wells
EUR 550

Horse Pancreas/Duodenum Homeobox Protein 1 (PDX1) ELISA Kit

MBS9362484-5x96StripWells 5x96-Strip-Wells
EUR 3420

Horse Pancreas/Duodenum Homeobox Protein 1 (PDX1) ELISA Kit

MBS9362484-96StripWells 96-Strip-Wells
EUR 765

Plant Pancreas/Duodenum Homeobox Protein 1 (PDX1) ELISA Kit

MBS9378501-INQUIRE INQUIRE Ask for price

Mouse Pancreas/duodenum homeobox protein 1, PDX1 ELISA Kit

MBS9330775-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Pancreas/duodenum homeobox protein 1, PDX1 ELISA Kit

MBS9330775-48StripWells 48-Strip-Wells
EUR 550

Mouse Pancreas/duodenum homeobox protein 1, PDX1 ELISA Kit

MBS9330775-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Pancreas/duodenum homeobox protein 1, PDX1 ELISA Kit

MBS9330775-96StripWells 96-Strip-Wells
EUR 765

Camel Pancreas/Duodenum Homeobox Protein 1 (PDX1) ELISA Kit

MBS9346770-10x96StripWells 10x96-Strip-Wells
EUR 6725

Camel Pancreas/Duodenum Homeobox Protein 1 (PDX1) ELISA Kit

MBS9346770-48StripWells 48-Strip-Wells
EUR 550

Camel Pancreas/Duodenum Homeobox Protein 1 (PDX1) ELISA Kit

MBS9346770-5x96StripWells 5x96-Strip-Wells
EUR 3420

Camel Pancreas/Duodenum Homeobox Protein 1 (PDX1) ELISA Kit

MBS9346770-96StripWells 96-Strip-Wells
EUR 765

Mouse Pancreas/Duodenum Homeobox Protein 1 (PDX1) ELISA Kit

MBS9347455-10x96StripWells 10x96-Strip-Wells
EUR 6725

Using A549 lung most cancers cells, concentration-response profiling of a pharmaceutical compound, the fatty acid synthase inhibitor GSK2194069, are demonstrated. Direct cell tradition on DMAs permits mixture of microscopy and excessive velocity, excessive molecular content material evaluation utilizing MALDI-MSI. Miniaturization of array spots all the way down to 0.5 mm confining 40 nL droplets permits for MALDI imaging evaluation of as few as ten cells per spot. Partial automation ensures a quick pattern preparation workflow. Taken collectively, the built-in DMA-MSI platform that mixes MALDI-MSI, as a label-free analytical readout, with the miniaturized droplet microarray platform is a worthwhile complement to excessive throughput cell-based assays applied sciences.